Single-strand template repair: key insights to increase the efficiency of gene editing

Author:

Gallagher Danielle N.,Haber James E.ORCID

Funder

Foundation for the National Institutes of Health

National Science Foundation

Publisher

Springer Science and Business Media LLC

Subject

Genetics,General Medicine

Reference47 articles.

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2. Canny MD, Moatti N, Wan LCK, Fradet-Turcotte A, Krasner D, Mateos-Gomez PA et al (2017) Inhibition of 53BP1 favors homology-dependent DNA repair and increases CRISPR-Cas9 genome-editing efficiency. Nat Biotechnol 25:95–102

3. Charpentier M, Khedher AHY, Menoret S, Brion A, Lamribet K, Dardillac E et al (2018) CtIP fusion to Cas9 enhances transgene integration by homology dependent repair. Nat Commun 9:1133

4. Chen Z, Yang H, Pavletich NP (2008) Mechanism of homologous recombination from the RecA-ssDNA/dsDNA structures. Nature 453:484–489

5. Datta A, Adjiri A, New L, Crouse GF, Jinks-Robertson S (1996) Mitotic crossovers between diverged sequences are regulated by mismatch repair proteins in Saccharomyces cerevisiae. Mol Cell Biol 16:1085–1093

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