Onkolytische Viren zur Behandlung von Krebserkrankungen

Abstract

AbstractOncolytic virotherapy is a promising immunotherapeutic strategy in the ongoing quest for effective cancer treatments. Anti-tumor effects are achieved by direct destruction of cancer cells, leading to the release of tumor antigens and the induction of an anti-tumor immune response. Preclinical research is focused on combining and genetically modifying oncolytic viruses to further improve their safety and potency. Here, we discuss some of the manifold approaches of viral engineering.