Author:
Jendrossek Dieter,Hildenbrand Jennie C.
Abstract
AbstractPolyphosphate (polyP) is an inorganic biopolymer ubiquitously present in all species. It has a variety of functions ranging from that of a reservoir for phosphorous in many microorganisms to functions in blood coagulation and plays a role in neurogenerative diseases in humans. Here, we provide a summary of the structure and functions that have been addressed to polyP in microorganisms.
Publisher
Springer Science and Business Media LLC
Subject
Molecular Biology,Biotechnology
Reference14 articles.
1. Jessen HJ, Dürr-Mayer T, Haas TM et al (2021) Lost in condensation: poly-, cyclo-, and ultraphosphates. Acc Chem Res 54: 4036–4050
2. Rao NN, Gómez-García MR, Kornberg A (2009) Inorganic polyphosphate: essential for growth and survival. Annu Rev Biochem 78: 605–647
3. Neville N, Roberge N, Jia Z (2022) Polyphosphate kinase 2 (PPK2) enzymes: structure, function, and roles in bacterial physiology and virulence. Int J Mol Sci 23: 670
4. Frank C, Teleki A, Jendrossek D (2020) Characterization of Agrobacterium tumefaciens PPKs reveals the formation of oligophosphorylated products up to nucleoside nona-phosphates. Appl Microbiol Biotechnol 265: 11734–11710
5. Hildenbrand JC, Teleki A, Jendrossek D (2020) A universal polyphosphate kinase: PPK2c of Ralstonia eutropha accepts purine and pyrimidine nucleotides including uridine diphosphate. Appl Microbiol Biotechnol 265: 11734–11739