Author:
Elter Adrian,Bogen Jan P.,Habermann Jan,Kolmar Harald
Abstract
AbstractDue to the large evolutionary distance between birds (Aves) und humans, immunization of chickens with human proteins results in a strong response of the bird’s adaptive immune system to proteins of mammalian origin. Additionally, chicken-derived antibodies display less undesired cross-reactivity in analytical setups than conventional rodent-derived antibodies. Due to these features as well as the facile amplification of antibody-coding genes, chicken-derived antibodies emerged as promising molecules for the immunotherapy and various biotechnological applications.
Publisher
Springer Science and Business Media LLC
Subject
Molecular Biology,Biotechnology
Cited by
1 articles.
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