Therapieverbesserung bei Vergiftung mit phosphororganischen Verbindungen
Author:
Publisher
Springer Science and Business Media LLC
Subject
Molecular Biology,Biotechnology
Link
http://link.springer.com/content/pdf/10.1007/s12268-019-1055-5.pdf
Reference12 articles.
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2. Elsinghorst PW, Worek F, Thiermann H et al. (2013) Drug development for the management of organophosphorus poisoning. Expert Opin Drug Discov 8:1467–1477
3. Wille T, Ekström F, Lee J-C et al. (2010) Kinetic analysis of interactions between alkylene-linked bis-pyridiniumaldoximes and human acetylcholinesterases inhibited by various organophosphorus compounds. Biochem Pharmacol 80:941–946
4. Worek F, Bierwisch A, Wille T et al. (2012) Kinetic interactions of a homologous series of bispyridinium monooximes (HGG oximes) with native and phosphonylated human acetylcholinesterase. Toxicol Lett 212:29–32
5. Worek F, Koller M, Thiermann H et al. (2016) Reactivation of nerve agent-inhibited human acetylcholinesterase by obidoxime, HI-6 and obidoxime +HI-6. Kinetic in vitro study with simulated nerve agent toxicokinetics and oxime pharmacokinetics. Toxicology 350–352:25–30
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