Immungenetik beeinflusst Infektion und Verlauf von COVID-19

Author:

Lehmann Claudia,Doxiadis Ilias

Abstract

AbstractIn the present report, we concentrate on the influence of immunogenetics on the SARS-CoV-2 infection. A total of 527 SARS-CoV-2 PCR positive and negative individuals from Saxony was investigated. We used NGS for HLA-A, B, C, DRB1, DRB345, DQA1, DQB1, DPA1, andDPB1typing. Then, we defined 26 genes and 5 platelet genes. Here we discuss possible predisposition of individuals expressing specific HLA alleles or combinations.

Publisher

Springer Science and Business Media LLC

Subject

Molecular Biology,Biotechnology

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