Author:
Bigalke Arite,Krüger Thomas,Jia Lei-Jie,Kniemeyer Olaf,Brakhage Axel A.
Abstract
AbstractAspergillus fumigatus is a medically important human pathogenic fungus. It can cause various diseases such as serious allergic reactions and life-threatening, invasive infections. Proteome analyses massively contribute to elucidating host-pathogen interactions. Here, we describe challenges to analyze host-pathogen interactions using mass spectrometry-based proetomics; we provide insights into our research findings and current understanding about the role of proteins from both the fungus and human immune cells during infections.
Publisher
Springer Science and Business Media LLC
Subject
Molecular Biology,Biotechnology