Wie Zellen kommunizieren: extra-zelluläre Vesikel als Signalübermittler

Abstract

AbstractDevelopment and homeostasis of multicellular organisms requires a constant exchange of information. Intercellular communication can be mediated by extracellular vesicles — tightly packed informational units that are secreted by virtually all cell types. Depending on their origin they carry distinct sets of proteins and RNAs and elicit diverse signalling responses in close and distant target cells. Despite their crucial role for health and disease, their biogenesis remains poorly understood.