Author:
Selim Khaled A.,Zimmer Erik
Abstract
AbstractPII superfamily consists of signal transduction proteins found in all domains of life. PII-like proteins evolved to fulfill diverse, yet poorly understood cellular functions. We recently identified the PII-like protein SbtB in cyanobacteria as a sensor of various adenine nucleotides including the second messengers cAMP and c-di-AMP. This highlights SbtB as a central switch-point in cyanobacterial physiology, integrating not only signals from the energy state and carbon supply, but also signals from the day/night status, to regulate the glycogen metabolism.
Publisher
Springer Science and Business Media LLC
Subject
Molecular Biology,Biotechnology