1. Buckett, W.R., Hopcroft, R.H., Luscombe, G.P., and Thomas, P.C. (1987a). BTS 54 524, a monoamine uptake inhibitor exhibiting potent actions in models predictive of potential antidepressant activity. Br. J. Pharmac., 90, in press.
2. Buckett, W.R., Luscombe, G.P., Thomas, P.C. (1987b). The putative antidepressant BTS 54 524 rapidly and potently down-regulates cortical β-adrenoceptors in the rat. Br. J Pharmac., 90, in press.
3. Hollister, L.E. (1986). Current antidepressants. Ann. Rev. Pharmacol. Toxicol., 26, 23–37.
4. Mobley, P.L., and Sulser, F. (1981). Down-regulation of the central noradrenergic system by antidepressant therapies: biochemical and chemical aspects. In Enna, S.J., Malick, J.B., and Richelson, E. (eds.), Antidepressants: Neurochemical, Behavioral and Clinical Perspectives, Raven, New York, 31–45.
5. Ostrow, D. (1985). The new generation antidepressants: promising innovations or disappointments? J. Clin. Psychiatry, 46, suppl. 2, 6–24.