Fully-Automatic 3D Intuitive Visualization of Age-Related Macular Degeneration Fluid Accumulations in OCT Cubes
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Published:2022-05-05
Issue:5
Volume:35
Page:1271-1282
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ISSN:0897-1889
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Container-title:Journal of Digital Imaging
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language:en
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Short-container-title:J Digit Imaging
Author:
López-Varela Emilio, Vidal Plácido L.ORCID, Pascual Nuria Olivier, Novo Jorge, Ortega Marcos
Abstract
AbstractAge-related macular degeneration is the leading cause of vision loss in developed countries, and wet-type AMD requires urgent treatment and rapid diagnosis because it causes rapid irreversible vision loss. Currently, AMD diagnosis is mainly carried out using images obtained by optical coherence tomography. This diagnostic process is performed by human clinicians, so human error may occur in some cases. Therefore, fully automatic methodologies are highly desirable adding a layer of robustness to the diagnosis. In this work, a novel computer-aided diagnosis and visualization methodology is proposed for the rapid identification and visualization of wet AMD. We adapted a convolutional neural network for segmentation of a similar domain of medical images to the problem of wet AMD segmentation, taking advantage of transfer learning, which allows us to work with and exploit a reduced number of samples. We generate a 3D intuitive visualization where the existence, position and severity of the fluid were represented in a clear and intuitive way to facilitate the analysis of the clinicians. The 3D visualization is robust and accurate, obtaining satisfactory 0.949 and 0.960 Dice coefficients in the different evaluated OCT cube configurations, allowing to quickly assess the presence and extension of the fluid associated to wet AMD.
Funder
Instituto de Salud Carlos III Ministerio de Ciencia e Innovación y Universidades Ministerio de Ciencia e Innovación, Gobierno de España Consellería de Cultura, Educación e Universidade, Xunta de Galicia Ayudas para la Formaciṕn del Profesorado Universitario (FPU) Universidade da Coruña
Publisher
Springer Science and Business Media LLC
Subject
Computer Science Applications,Radiology, Nuclear Medicine and imaging,Radiological and Ultrasound Technology
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