Chronic Demyelination and Axonal Degeneration in Multiple Sclerosis: Pathogenesis and Therapeutic Implications

Author:

Simkins Tyrell JORCID,Duncan Greg J,Bourdette Dennis

Publisher

Springer Science and Business Media LLC

Subject

Neurology (clinical),General Neuroscience

Reference122 articles.

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2. Wallin MT, Culpepper WJ, Campbell JD, Nelson LM, Langer-Gould A, Marrie RA, et al. The prevalence of MS in the United States: a population-based estimate using health claims data. Neurology. 2019;92(10):e1029–e40. https://doi.org/10.1212/WNL.0000000000007035.

3. Feigin VL, Abajobir AA, Abate KH, Abd-Allah F, Abdulle AM, Abera SF, et al. Global, regional, and national burden of neurological disorders during 1990–2015: a systematic analysis for the Global Burden of Disease Study 2015. The Lancet Neurology. 2017;16(11):877–97. https://doi.org/10.1016/s1474-4422(17)30299-5.

4. • Paz-Zulueta M, Parás-Bravo P, Cantarero-Prieto D, Blázquez-Fernández C, Oterino-Durán A. A literature review of cost-of-illness studies on the economic burden of multiple sclerosis. Multiple Sclerosis and Related Disorders. 2020;43:102162. https://doi.org/10.1016/j.msard.2020.102162This review details the evidence demonstrating the well-known large economic burden of multiple sclerosis, highlighting the continued need for improved therapies and outcomes.

5. Rommer PS, Milo R, Han MH, Satyanarayan S, Sellner J, Hauer L, et al. Immunological aspects of approved MS therapeutics. Front Immunol. 2019;10:1564. https://doi.org/10.3389/fimmu.2019.01564.

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