An Overview of Alternating Electric Fields Therapy (NovoTTF Therapy) for the Treatment of Malignant Glioma-Reference-Cited by-同舟云学术

An Overview of Alternating Electric Fields Therapy (NovoTTF Therapy) for the Treatment of Malignant Glioma

Published:2016-01 Issue:1 Volume:16 Page:
ISSN:1528-4042
Container-title:Current Neurology and Neuroscience Reports
language:en
Short-container-title:Curr Neurol Neurosci Rep

Author:

Swanson Kenneth D.,Lok Edwin,Wong Eric T.

Publisher

Springer Science and Business Media LLC

Subject

Clinical Neurology,General Neuroscience

Link

http://link.springer.com/content/pdf/10.1007/s11910-015-0606-5.pdf

Reference53 articles.

1. Kirson ED, Dbaly V, Tovarys F, Vymazal J, Soustiel JF, Itzhaki A, et al. Alternating electric fields arrest cell proliferation in animal tumor models and human brain tumors. Proc Natl Acad Sci U S A. 2007;104:10152–7. Describes the first-in-human application of the NovoTTF therapy device to patients with recurrent glioblastoma.

2. Kirson ED, Gurvich Z, Schneiderman R, Dekel E, Itzhaki A, Wasserman Y, et al. Disruption of cancer cell replication by alternating electric fields. Cancer Res. 2004;64:3288–95. Describes the initial observation of the effect of alternating electric fields on tubulin disorder in cell culture experiments.

3. Gera N, Yang A, Holtzman TS, Lee SX, Wong ET, Swanson KD. Tumor treating fields perturb the localization of septins and cause aberrant mitotic exit. PLoS ONE. 2015;10, e0125269. This paper establishes that septin is disrupted during exposure to alternating electric fields that results in violent cellular blebbing during metaphase to anaphase transition.

4. Lee SX, Wong ET, Swanson KD. Disruption of cell division within anaphase by tumor treating electric fields (TTFields) leads to immunogenic cell death. Neurooncology. 2013;15:iii66–7.

5. Kirson ED, Giladi M, Gurvich Z, Itzhaki A, Mordechovich D, Schneiderman RS, et al. Alternating electric fields (TTFields) inhibit metastatic spread of solid tumors to the lungs. Clin Exp Metastasis. 2009;26:633–40.

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