N-Nitrosodiethanolamine is activated in the rat to an ultimate genotoxic metabolite by sulfotransferase

Author:

Sterzel W.,Eisenbrand G.

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology,General Medicine

Reference20 articles.

1. Airoldi L, Bonfanti M, Benfenati E, Tavecchia P, Fanelli R (1983) Identification of an acidic metabolite of N-nitrosodiethanolamine isolated from rat urine. Biomed Mass Spectrom 10:334?337

2. Denkel E, Pool BL, Sterzel W, Eisenbrand G (1985) Biological activity of potential metabolites of N-nitrosodiethanolamine which may arise after activation by alcohol dehydrogenase. Proceedings of the 4th Int Conf on Environ mutagens, Stockholm

3. De Meio RM (1975) Sulfate activation and transfer. In: Greenberg DM (ed) Metabolism of sulfur compounds. Academic Press, New York, pp 287?358

4. Druckrey H, Preussmann R, Ivankovic S, Schm�hl D (1967) Organotrophe carcinogene Wirkung bei 65 verschiedenen N-Nitrosoverbindungen an BD-Ratten. Z Krebsforsch 69:103?201

5. Eisenbrand G, Denkel E, Pool B (1984) Alcohol dehydrogenase as an activating enzyme for N-nitrosodiethanolamine (NDELA): In vitro activation of NDELA to a potent mutagen in Salmonella typhimurium. J Cancer Res Clin Oncol 108:76?80

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