Cytogenetical changes during early stages of development of methotrexate resistance in HeLa cells
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Oncology
Link
https://link.springer.com/content/pdf/10.1007/BF02934778.pdf
Reference15 articles.
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2. Alt F W, Kellems R E, Schimke R T: Synthesis and degradation of folate reductase in sensitive and methotrexate-resistant lines of S-180 cells.J Biol Chem 251, 3063 (1976).
3. Littlefield J W, Chang S E, Hänggi U J, Nakamura H, Orbin S H: Studies on the overproduction of DHFR by variant hamster cells in culture.Adv Enzyme Regul 15, 301 (1977).
4. Curt G A, Carney D N, Cowan K H, Jolivet J, Bailey B D, Drake J C, Kao-Shan C S, Minna J D, Chabner B A: Unstable MTX-resistance in human small-cell carcinoma associated with double minute chromosomes.New Engl J Med 308, 199 (1983).
5. Bostock C J, Clark E M, Harding N G, Mounts P M, Tyler-Smith C, Van Heyrringen V, Walker P M: The development of resistance to methotrexate in a mouse melanoma cell line. I. Characterization of the dihydrofolate reductases and chromosomes in sensitive and resistant cells.Chromosoma (Berl.) 74, 153 (1979).
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