Targeted elimination of mutant mitochondrial DNA in MELAS-iPSCs by mitoTALENs-Reference-Cited by-同舟云学术

Targeted elimination of mutant mitochondrial DNA in MELAS-iPSCs by mitoTALENs

Published:2018-01-09 Issue:3 Volume:9 Page:283-297
ISSN:1674-800X
Container-title:Protein & Cell
language:en
Short-container-title:Protein Cell

Author:

Yang Yi,Wu Han,Kang Xiangjin,Liang Yanhui,Lan Ting,Li Tianjie,Tan Tao,Peng Jiangyun,Zhang Quanjun,An Geng,Liu Yali,Yu Qian,Ma Zhenglai,Lian Ying,Soh Boon Seng,Chen Qingfeng,Liu Ping,Chen Yaoyong,Sun Xiaofang,Li Rong,Zhen Xiumei,Liu Ping,Yu Yang,Li Xiaoping,Fan Yong

Publisher

Springer Science and Business Media LLC

Subject

Cell Biology,Drug Discovery,Biochemistry,Biotechnology

Link

http://link.springer.com/article/10.1007/s13238-017-0499-y/fulltext.html

Reference34 articles.

1. Alexeyev MF, Venediktova N, Pastukh V, Shokolenko I, Bonilla G, Wilson GL (2008) Selective elimination of mutant mitochondrial genomes as therapeutic strategy for the treatment of NARP and MILS syndromes. Gene Ther 15(7):516–523

2. Anderson S, Bankier AT, Barrell BG, de Bruijn MH, Coulson AR, Drouin J, Eperon IC, Nierlich DP, Roe BA, Sanger F et al (1981) Sequence and organization of the human mitochondrial genome. Nature 290(5806):457–465

3. Bacman SR, Williams SL, Garcia S, Moraes CT (2010) Organ-specific shifts in mtDNA heteroplasmy following systemic delivery of a mitochondria-targeted restriction endonuclease. Gene Ther 17(6):713–720

4. Bacman SR, Williams SL, Pinto M, Peralta S, Moraes CT (2013) Specific elimination of mutant mitochondrial genomes in patient-derived cells by mitoTALENs. Nat Med 19(9):1111–1113

5. Boch J, Bonas U (2010) Xanthomonas AvrBs3 family-type III effectors: discovery and function. Annu Rev Phytopathol 48:419–436

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