Syntheses and Radiosyntheses of Two Carbon-11 Labeled Potent and Selective Radioligands for Imaging Vesicular Acetylcholine Transporter-Reference-Cited by-同舟云学术

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Syntheses and Radiosyntheses of Two Carbon-11 Labeled Potent and Selective Radioligands for Imaging Vesicular Acetylcholine Transporter

Published:2014-05-30 Issue:6 Volume:16 Page:765-772
ISSN:1536-1632
Container-title:Molecular Imaging and Biology
language:en
Short-container-title:Mol Imaging Biol

Author:

Padakanti Prashanth K.,Zhang Xiang,Li Junfeng,Parsons Stanley M.,Perlmutter Joel S.,Tu Zhude

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Radiology Nuclear Medicine and imaging,Oncology

Link

http://link.springer.com/content/pdf/10.1007/s11307-014-0748-x.pdf

Reference25 articles.

1. Schliebs R, Arendt T (2006) The significance of the cholinergic system in the brain during aging and in Alzheimer’s disease. J Neural Transm 113:1625–1644

2. Hilker R, Thomas AV, Klein JC et al (2005) Dementia in Parkinson disease: functional imaging of cholinergic and dopaminergic pathways. Neurology 65:1716–1722

3. Gilmor ML, Nash NR, Roghani A et al (1996) Expression of the putative vesicular acetylcholine transporter in rat brain and localization in cholinergic synaptic vesicles. J Neurosci 16:2179–2190

4. Prado VF, Martins-Silva C, de Castro BM et al (2006) Mice deficient for the vesicular acetylcholine transporter are myasthenic and have deficits in object and social recognition. Neuron 51:601–612

5. Rogers GA, Parsons SM, Anderson DC et al (1989) Synthesis, in vitro acetylcholine-storage-blocking activities, and biological properties of derivatives and analogues of trans-2-(4-phenylpiperidino)cyclohexanol (vesamicol). J Med Chem 32:1217–1230

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