Spatial Concordance of Tumor Proliferation and Accelerated Repopulation from Pathologic Images to 3′-[18F]Fluoro-3′-Deoxythymidine PET Images: a Basic Study Guided for PET-Based Radiotherapy Dose Painting

Author:

Li Chengming,Zhang Xiaoli,Pang Linlin,Huang Yong,Gao Yongsheng,Sun Xindong,Yu Jinming,Meng XueORCID

Funder

National Natural Science Foundation of China

Science and Technology Development Plans of Shandong Province

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Radiology, Nuclear Medicine and imaging,Oncology

Reference17 articles.

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2. Brower JV, Amini A, Chen S, Hullett CR, Kimple RJ, Wojcieszynski AP, Bassetti M, Witek ME, Yu M, Harari PM, Baschnagel AM (2016) Improved survival with dose-escalated radiotherapy in stage III non-small-cell lung cancer: analysis of the national cancer database. Ann Oncol 27:1887–1894

3. Tucker SL, Liu A, Gomez D, Tang LL, Allen P, Yang J, Liao Z, Grosshans D (2016) Impact of heart and lung dose on early survival in patients with non-small cell lung cancer treated with chemoradiation. Radiother Oncol 119:495–500

4. Even AJ, van der Stoep J, Zegers CM et al (2015) PET-based dose painting in non-small cell lung cancer: comparing uniform dose escalation with boosting hypoxic and metabolically active sub-volumes. Radiother Oncol 116:281–286

5. Liu J, Li C, Hu M, Lu J, Shi X, Xing L, Sun X, Fu Z, Yu J, Meng X (2015) Exploring spatial overlap of high-uptake regions derived from dual tracer positron emission tomography computer tomography imaging using 18F-fluorodeoxyglucose and 18F-fluorodeoxythymidine in non-small cell lung cancer patients: a prospective pilot study. Medicine 94:e678

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