Imaging HDACs In Vivo: Cross-Validation of the [11C]Martinostat Radioligand in the Pig Brain
Author:
Funder
Lundbeckfonden
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Radiology, Nuclear Medicine and imaging,Oncology
Link
http://link.springer.com/content/pdf/10.1007/s11307-019-01403-9.pdf
Reference25 articles.
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3. Gilbert TM, Zürcher NR, Wu CJ, Bhanot A, Hightower BG, Kim M, Albrecht DS, Wey HY, Schroeder FA, Rodriguez-Thompson A, Morin TM, Hart KL, Pellegrini AM, Riley MM, Wang C, Stufflebeam SM, Haggarty SJ, Holt DJ, Loggia ML, Perlis RH, Brown HE, Roffman JL, Hooker JM (2018) PET neuroimaging reveals histone deacetylase dysregulation in schizophrenia. J Clin Invest 129:364–372. https://doi.org/10.1172/JCI123743
4. Wang C, Schroeder FA, Wey HY, Borra R, Wagner FF, Reis S, Kim SW, Holson EB, Haggarty SJ, Hooker JM (2014) In vivo imaging of histone deacetylases (HDACs) in the central nervous system and major peripheral organs. J Med Chem 57:7999–8009
5. Wey H-Y, Wang C, Schroeder FA, Schroeder FA, Logan J, Price JC, Hooker JM (2015) Kinetic analysis and quantification of [11C]Martinostat for in vivo HDAC imaging of the brain. ACS Chem Neurosci 6:708–715
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