Histone methyltransferase KMT2D inhibits ENKTL carcinogenesis by epigenetically activating SGK1 and SOCS1-Reference-Cited by-同舟云学术

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Histone methyltransferase KMT2D inhibits ENKTL carcinogenesis by epigenetically activating SGK1 and SOCS1

Published:2023-07-31 Issue:2 Volume:46 Page:203-212
ISSN:1976-9571
Container-title:Genes & Genomics
language:en
Short-container-title:Genes Genom

Author:

Zhang Yue-Hua,Tao Qing,Zhang Wen-Yan,Zhao Sha,Liu Wei-Ping,Gao Li-Min

Funder

National Natural Science Foundation of China

Sichuan Province Science and Technology Support Program

Publisher

Springer Science and Business Media LLC

Subject

Genetics,Molecular Biology,Biochemistry

Link

https://link.springer.com/content/pdf/10.1007/s13258-023-01434-1.pdf

Reference39 articles.

1. Alam H, Tang M, Maitituoheti M, Dhar SS, Kumar M, Han CY, Ambati CR, Amin SB, Gu B, Chen TY et al (2020) KMT2D Deficiency impairs super-enhancers to Confer a glycolytic vulnerability in Lung Cancer. Cancer Cell 37:599–617e597

2. Arber DA, Orazi A, Hasserjian R, Thiele J, Borowitz MJ, Le Beau MM, Bloomfield CD, Cazzola M, Vardiman JW (2016) The 2016 revision to the World Health Organization classification of myeloid neoplasms and acute leukemia. Blood 127:2391–2405

3. Ehrentraut S, Schneider B, Nagel S, Pommerenke C, Quentmeier H, Geffers R, Feist M, Kaufmann M, Meyer C, Kadin ME et al (2016) Th17 cytokine differentiation and loss of plasticity after SOCS1 inactivation in a cutaneous T-cell lymphoma. Oncotarget 7:34201–34216

4. Gao LM, Zhao S, Zhang WY, Wang M, Li HF, Lizaso A, Liu WP (2019) Somatic mutations in KMT2D and TET2 associated with worse prognosis in Epstein-Barr virus-associated T or natural killer-cell lymphoproliferative disorders. Cancer Biol Ther 20:1319–1327

5. Grasso CS, Wu YM, Robinson DR, Cao X, Dhanasekaran SM, Khan AP, Quist MJ, Jing X, Lonigro RJ, Brenner JC et al (2012) The mutational landscape of lethal castration-resistant prostate cancer. Nature 487:239–243

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