Simultaneous Screening of Glutathione and Cyanide Adducts Using Precursor Ion and Neutral Loss Scans-Dependent Product Ion Spectral Acquisition and Data Mining Tools-Reference-Cited by-同舟云学术

Simultaneous Screening of Glutathione and Cyanide Adducts Using Precursor Ion and Neutral Loss Scans-Dependent Product Ion Spectral Acquisition and Data Mining Tools

Published:2012-03-06 Issue:5 Volume:23 Page:964-976
ISSN:1044-0305
Container-title:Journal of the American Society for Mass Spectrometry
language:en
Short-container-title:J. Am. Soc. Mass Spectrom.

Author:

Jian Wenying¹,Liu Hua-Fen²,Zhao Weiping³,Jones Elliott²,Zhu Mingshe³

Affiliation:

1. Janssen Research and Development, Pharmaceutical Companies of Johnson and Johnson, Raritan, NJ, USA

2. AB SCIEX, Foster City, CA, USA

3. Department of Biotransformation, Bristol-Myers Squibb, Princeton, NJ, USA

Publisher

American Chemical Society (ACS)

Subject

Spectroscopy,Structural Biology

Link

http://link.springer.com/content/pdf/10.1007/s13361-012-0354-6.pdf

Reference45 articles.

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3. In Vitro Bioactivation of Dihydrobenzoxathiin Selective Estrogen Receptor Modulators by Cytochrome P450 3A4 in Human Liver Microsomes: Formation of Reactive Iminium and Quinone Type Metabolites

4. In Vitro Screening Techniques for Reactive Metabolites for Minimizing Bioactivation Potential in Drug Discovery

5. Analytical strategies for the screening and evaluation of chemically reactive drug metabolites

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