Substrate and Substrate-Mimetic Chaperone Binding Sites in Human α-Galactosidase A Revealed by Affinity-Mass Spectrometry-Reference-Cited by-同舟云学术

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Substrate and Substrate-Mimetic Chaperone Binding Sites in Human α-Galactosidase A Revealed by Affinity-Mass Spectrometry

Published:2016-04-25 Issue:6 Volume:27 Page:1071-1078
ISSN:1044-0305
Container-title:Journal of the American Society for Mass Spectrometry
language:en
Short-container-title:J. Am. Soc. Mass Spectrom.

Author:

Moise Adrian¹²,Maeser Stefan¹,Rawer Stephan³,Eggers Frederike²,Murphy Mary⁴,Bornheim Jeff⁴,Przybylski Michael¹²

Affiliation:

1. Steinbeis Center for Biopolymer Analysis and Biomedical Mass Spectrometry, 65428, Rüsselsheim am Main, Germany

2. Laboratory of Analytical Chemistry, University of Konstanz, 78457, Konstanz, Germany

3. ThermoFisher Scientific, Franfurter Strasse 129, 64269, Darmstadt, Germany

4. Ametek-Reichert Technologies, 3362 Walden Avenue, 14043, Buffalo, NY, USA

Funder

Bundesministerium fur Wirtschaft und Technologie

Publisher

American Chemical Society (ACS)

Subject

Spectroscopy,Structural Biology

Link

http://link.springer.com/content/pdf/10.1007/s13361-016-1386-0.pdf

Reference26 articles.

1. Synthesis and processing of alpha-galactosidase A in human fibroblasts. Evidence for different mutations in Fabry disease.

2. A synthetic chaperone corrects the trafficking defect and disease phenotype in a protein misfolding disorder

3. Agalsidase alfa – a preparation for enzyme replacement therapy in Anderson–Fabry disease

4. The Molecular Defect Leading to Fabry Disease: Structure of Human α-Galactosidase

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1. Identification of dual active sites in Caenorhabditis elegans GANA-1 protein: an ortholog of the human α-GAL a and α-NAGA enzymes;Journal of Biomolecular Structure and Dynamics;2022-06-11

2. Identification and Affinity Determination of Protein-Antibody and Protein-Aptamer Epitopes by Biosensor-Mass Spectrometry Combination;International Journal of Molecular Sciences;2021-11-27

3. Endolysosomal N-glycan processing is critical to attain the most active form of the enzyme acid alpha-glucosidase;Journal of Biological Chemistry;2021-01

4. Antibody Epitope and Affinity Determination of the Myocardial Infarction Marker Myoglobin by SPR-Biosensor Mass Spectrometry;Journal of the American Society for Mass Spectrometry;2020-08-03

5. Molecular Epitope Determination of Aptamer Complexes of the Multidomain Protein C‐Met by Proteolytic Affinity‐Mass Spectrometry;ChemMedChem;2020-02-17

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