The Clinicopathological and Molecular Associations of PD-L1 Expression in Non-small Cell Lung Cancer: Analysis of a Series of 10,005 Cases Tested with the 22C3 Assay

Author:

Evans MatthewORCID,O’Sullivan Brendan,Hughes Frances,Mullis Tina,Smith Matthew,Trim Nicola,Taniere Philippe

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology,General Medicine,Pathology and Forensic Medicine

Reference50 articles.

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2. Herbst RS, Baas P, Kim DW, Felip E, Perez-Gracia JL, Han JY, Molina J, Kim JH, Arvis CD, Ahn MJ, Majem M, Fidler MJ, de Castro G Jr, Garrido M, Lubiniecki GM, Shentu Y, Im E, Dolled-Filhart M, Garon EB (2016) Pembrolizumab versus docetaxel for previously treated, PD-L1-positive, advanced non-small-cell lung cancer (KEYNOTE-010): a randomised controlled trial. Lancet 387(10027):1540–1550. https://doi.org/10.1016/S0140-6736(15)01281-7

3. Garon EB, Rizvi NA, Hui R, Leighl N, Balmanoukian AS, Eder JP, Patnaik A, Aggarwal C, Gubens M, Horn L, Carcereny E, Ahn MJ, Felip E, Lee JS, Hellmann MD, Hamid O, Goldman JW, Soria JC, Dolled-Filhart M, Rutledge RZ, Zhang J, Lunceford JK, Rangwala R, Lubiniecki GM, Roach C, Emancipator K, Gandhi L, Investigators K (2015) Pembrolizumab for the treatment of non-small-cell lung cancer. N Engl J Med 372(21):2018–2028. https://doi.org/10.1056/NEJMoa1501824

4. Cho J, Zhou W, Choi YL, Sun JM, Choi H, Kim TE, Dolled-Filhart M, Emancipator K, Rutkowski MA, Kim J (2015) 26OMolecular epidemiology study of PD-L1 expression in patients (pts) with EGFR-mutant NSCLC. Ann Oncol 26(suppl_9):ix8. https://doi.org/10.1093/annonc/mdv518.01

5. Salanova R, Pereyra JCC, Leguina L, Bena A, Barberis M, Vargas R, RJd T, Kreimberg K, Powazniak Y (2017) Epidemiology of PD-L1 and ALK expression and EGFR mutational status in Argentinian patients with lung cancer. J Clin Oncol 35(15_suppl):e20565. https://doi.org/10.1200/JCO.2017.35.15_suppl.e20565

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