Denosumab—A Powerful RANKL Inhibitor to Stop Lytic Metastases and Other Bone Loss Actions by Osteoclasts
Author:
Publisher
Springer Science and Business Media LLC
Subject
Cancer Research,Oncology,General Medicine,Pathology and Forensic Medicine
Link
http://link.springer.com/content/pdf/10.1007/s12253-012-9538-4.pdf
Reference35 articles.
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2. Brown JE, Coleman RE (2011) Denosumab in patients with cancer—a surgical strike against the osteoclast. Nature Rev Clin Oncol 9:110–118
3. Martin T, Gooi JH, Sims NA (2009) Molecular mechanisms in coupling of bone formation to resorption. Crit Rev Eukaryot Gene Expr 19:73–88
4. Bruzzaniti A, Baron R (2006) Molecular regulation of osteoclast activity. Rev J Endocr Metab Disord 7:123–139
5. Theoleyre S, Wittrant Y, Tat SK et al (2004) The molecular triad OPR/RANK/RANKL involvement in the orchestration of pathophysiological bone remodeling. Cytokine Growth Factor Rev 15:457–475
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