Outpatient Treatment with AZD7442 (Tixagevimab/Cilgavimab) Prevented COVID-19 Hospitalizations over 6 Months and Reduced Symptom Progression in the TACKLE Randomized Trial

Author:

Hobbs F. D. Richard,Montgomery Hugh,Padilla Francisco,Simón-Campos Jesus Abraham,Kim Kenneth,Arbetter Douglas,Padilla Kelly W.,Reddy Venkatesh Pilla,Seegobin Seth,Streicher Katie,Templeton Alison,Viani Rolando M.,Johnsson Eva,Koh Gavin C. K. W.,Esser Mark T.

Funder

AstaZeneca

Publisher

Springer Science and Business Media LLC

Subject

Infectious Diseases,Microbiology (medical)

Reference36 articles.

1. Our World in Data. Coronavirus (COVID-19) hospitalizations. 2022. https://ourworldindata.org/covid-hospitalizations. Accessed 8 Nov 2022.

2. Office for National Statistics. Direct and indirect health impacts of COVID-19 in England: emerging Omicron impacts. 2022. https://www.gov.uk/government/publications/direct-and-indirect-health-impacts-of-covid-19-in-england-emerging-omicron-impacts/direct-and-indirect-health-impacts-of-covid-19-in-england-emerging-omicron-impacts. Accessed 8 Nov 2022.

3. Centers for Disease Control and Prevention. COVID-NET: COVID-19-associated hospitalization surveillance network. 2022. https://gis.cdc.gov/grasp/covidnet/covid19_5.html. Accessed 8 Nov 2022.

4. Antonelli M, Penfold RS, Merino J, et al. Risk factors and disease profile of post-vaccination SARS-CoV-2 infection in UK users of the COVID Symptom Study app: a prospective, community-based, nested, case–control study. Lancet Infect Dis. 2022;22:43–55.

5. Chen C, Haupert SR, Zimmermann L, Shi X, Fritsche LG, Mukherjee B. Global prevalence of post-coronavirus disease 2019 (COVID-19) condition or long COVID: a meta-analysis and systematic review. J Infect Dis. 2022;226(9):1593–607.

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