HIV-1 Virologic Rebound Due to Coadministration of Divalent Cations and Bictegravir

Author:

Rock Alex E.,DeMarais Patricia L.,Vergara-Rodriguez Pamala T.,Max Blake E.

Publisher

Springer Science and Business Media LLC

Subject

Infectious Diseases,Microbiology (medical)

Reference29 articles.

1. Panel on Antiretroviral Guidelines for Adults and Adolescents. Guidelines for the Use of Antiretroviral Agents in Adults and Adolescents with HIV. Department of Health and Human Services. Available at http://www.aidsinfo.nih.gov/ContentFiles/AdultandAdolescentGL.pdf. Accessed 15 May 2020 [Table 6a, Table 21d].

2. Hajimahdi Z, Zarghi A. Progress in HIV-1 integrase inhibitors: a review of their chemical structure diversity. Iran J Pharm Res. 2016;15(4):595–628.

3. Song I, Borland J, Arya N, Wynne B, Piscitelli S. Pharmacokinetics of dolutegravir when administered with mineral supplements in healthy adult subjects. J Clin Pharmacol. 2015;55(5):490–6.

4. Krishna R, East L, Larson P, et al. Effect of metal-cation antacids on the pharmacokinetics of 1200 mg raltegravir. J Pharm Pharmacol. 2016;68(11):1359–65.

5. Forst TM, Dinges WL. Coadministration of divalent cation mineral supplements causes CART virologic failure and hiv mutagenesis: a Case Study. Clin J HIV AIDS. 2018;2(1):26–7.

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