Diphenylmethyl deprotection in continuous flow and its application in synthesis of β-lactam antibiotics
Author:
Publisher
Springer Science and Business Media LLC
Subject
Organic Chemistry,Fluid Flow and Transfer Processes,Chemistry (miscellaneous)
Link
https://link.springer.com/content/pdf/10.1007/s41981-021-00198-7.pdf
Reference19 articles.
1. Hideaki Y, Toshiyuki C, Kohji K, Hisashi T, Takashi M, Takao T (1985) Studies on beta-lactam antibiotics. IX. Synthesis and biological activity of a new orally active cephalosporin, cefixime (FK027). J Antibiot 38(12):1738–1751
2. Bernasconi E, Genders D, Lee J, Longoni D, Martin CR, Menon V, Roletto J, Sogli L, Walker D, Zappi G, Zelenay P, Zhang HY (2002) Ceftibuten: development of a commercial process based on cephalosporin C. Part II. Process for the manufacture of 3-Exomethylene-7(R)-glutaroylaminocepham-4-carboxylic Acid 1(S)-Oxide. Org Process Res Dev 6(2):158–168
3. Kirst HA, Toth JE, Wind JA, Debono M, Willard KE, Molloy RM, Paschal JW, Ott JL, Feltyduckworth AM, Counter FT (1986) Synthesis and structure-activity relationships of a new series of cephalosporins, BMY-28142 and related compounds. J Antibiot 39(8):1092–1107
4. Bywood R, Gallagher G, Sharma GK, Walker D (1975) Amino-acids and peptides. Part I. esterification of the carboxy-group of penicillins and cephalosporins by hydrazone oxidation. J Chem Soc Perkin I 7(3):2019–2022
5. Lapatsanis L, Milias G, Paraskewas S (1985) A simple method for the preparation of diphenylmethyl esters of N-protected amino acids. Synthesis 05:513–515
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