Protein C zymogen in severe sepsis: a double-blinded, placebo-controlled, randomized study-Reference-Cited by-同舟云学术

Protein C zymogen in severe sepsis: a double-blinded, placebo-controlled, randomized study

Published:2016-06-25 Issue:11 Volume:42 Page:1706-1714
ISSN:0342-4642
Container-title:Intensive Care Medicine
language:en
Short-container-title:Intensive Care Med

Author:

Pappalardo Federico,Crivellari Martina^ORCID,Di Prima Ambra L.,Agracheva Nataliya,Celinska-Spodar Malgorzata,Lembo Rosalba,Taddeo Daiana,Landoni Giovanni,Zangrillo Alberto

Funder

Italian Ministry of Health

Publisher

Springer Science and Business Media LLC

Subject

Critical Care and Intensive Care Medicine

Link

http://link.springer.com/content/pdf/10.1007/s00134-016-4405-5.pdf

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2. Gaieski DF, Edwards JM, Kallan MJ, Carr BG (2013) Benchmarking the incidence and mortality of severe sepsis in the United States. Crit Care Med 41:1167–1174. doi: 10.1097/CCM.0b013e31827c09f8

3. Brun-Buisson C, Meshaka P, Pinton P, Vallet B (2004) EPISEPSIS Study Group: EPISEPSIS: a reappraisal of the epidemiology and outcome of severe sepsis in French intensive care units. Intensive Care Med 30:580–588. doi: 10.1007/s00134-003-2121-4

4. Hotchkiss RS, Karl IE (2003) The pathophysiology and treatment of sepsis. N Engl J Med 348:138–150. doi: 10.1056/NEJMra021333

5. Bernard GR, Vincent JL, Laterre PF et al (2001) Efficacy and safety of recombinant human activated protein C for severe sepsis. N Engl J Med 344:699–709. doi: 10.1056/NEJM200103083441001

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