Targeting IL-6 and RANKL signaling inhibits prostate cancer growth in bone-Reference-Cited by-同舟云学术

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Targeting IL-6 and RANKL signaling inhibits prostate cancer growth in bone

Published:2014-09-16 Issue:8 Volume:31 Page:921-933
ISSN:0262-0898
Container-title:Clinical & Experimental Metastasis
language:en
Short-container-title:Clin Exp Metastasis

Author:

Zheng Yu,Basel Dennis,Chow Shu-Oi,Fong-Yee Colette,Kim Sarah,Buttgereit Frank,Dunstan Colin R.,Zhou Hong,Seibel Markus J.

Publisher

Springer Science and Business Media LLC

Subject

Cancer Research,Oncology,General Medicine

Link

http://link.springer.com/content/pdf/10.1007/s10585-014-9680-3.pdf

Reference56 articles.

1. Coleman RE (2001) Metastatic bone disease: clinical features, pathophysiology and treatment strategies. Cancer Treat Rev 27(3):165–176

2. Weilbaecher KN, Guise TA, McCauley LK (2011) Cancer to bone: a fatal attraction. Nat Rev Cancer 11(6):411–425

3. Zheng Y, Zhou H, Brennan K, Blair JM, Modzelewski JR, Seibel MJ, Dunstan CR (2007) Inhibition of bone resorption, rather than direct cytotoxicity, mediates the anti-tumour actions of ibandronate and osteoprotegerin in a murine model of breast cancer bone metastasis. Bone 40(2):471–478

4. Neudert M, Fischer C, Krempien B, Bauss F, Seibel MJ (2003) Site-specific human breast cancer (MDA-MB-231) metastases in nude rats: model characterisation and in vivo effects of ibandronate on tumour growth. Int J Cancer 107(3):468–477

5. Armstrong AP, Miller RE, Jones JC, Zhang J, Keller ET, Dougall WC (2008) RANKL acts directly on RANK-expressing prostate tumor cells and mediates migration and expression of tumor metastasis genes. Prostate 68(1):92–104

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