Isocyclopamine, a novel synthetic derivative of cyclopamine, reverts doxorubicin resistance in MCF-7/ADR cells by increasing intracellular doxorubicin accumulation and downregulating breast cancer stem-like cells

Author:

Liu Ming,Zhang Weiyi,Tang Wei,Wang Yanjuan,Zhao Xingzeng,Wang Xiangyun,Qi Xin,Li Jing

Publisher

Springer Science and Business Media LLC

Subject

General Medicine

Reference31 articles.

1. Faneyte IF, Kristel PMP, Maliepaard M, Scheffer GL, Scheper RJ, Schellens JHM, et al. Expression of the breast cancer resistance protein in breast cancer. Clin Cancer Res. 2002;8(4):1068–74.

2. Vasconcelos FC, Cavalcanti GB, Silva KL, Ed M, Kwee JK, Rumjanek VM, et al. Contrasting features of MDR phenotype in leukemias by using two fluorochromes: implications for clinical practice. Leuk Res. 2007;31(4):445–54. doi: 10.1016/j.leukres.2006.07.016 .

3. Legrand O, Simonin G, Beauchamp-Nicoud A, Zittoun R, Marie J-P. Simultaneous activity of MRP1 and Pgp is correlated with in vitro resistance to daunorubicin and with in vivo resistance in adult acute myeloid leukemia, vol. 3. 1999.

4. Sotiropoulou PA, Christodoulou MS, Silvani A, Herold-Mende C, Passarella D. Chemical approaches to targeting drug resistance in cancer stem cells. Drug Discov Today. 2014;19(10):1547–62. http://dx.doi.org/10.1016/j.drudis.2014.05.002 .

5. Mannello F. Understanding breast cancer stem cell heterogeneity: time to move on to a new research paradigm. BMC Med. 2013;11(1):169.

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