Protective effects of apigenin on altered lipid peroxidation, inflammation, and antioxidant factors in methotrexate-induced hepatotoxicity
Author:
Funder
Ahvaz Jundishapur University of Medical Sciences
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology,General Medicine
Link
https://link.springer.com/content/pdf/10.1007/s00210-020-01991-2.pdf
Reference77 articles.
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2. Ali F, Naz F, Jyoti S, Siddique YH (2014a) Protective effect of apigenin against N-nitrosodiethylamine (NDEA)-induced hepatotoxicity in albino rats. Mutat Res Genet Toxicol Environ Mutagen 767:13–20
3. Ali N, Rashid S, Nafees S, Hasan SK, Sultana S (2014b) Beneficial effects of Chrysin against Methotrexate-induced hepatotoxicity via attenuation of oxidative stress and apoptosis. Mol Cell Biochem 385:215–223
4. Androutsopoulos VP, Spandidos DA (2013) The flavonoids diosmetin and luteolin exert synergistic cytostatic effects in human hepatoma HepG2 cells via CYP1A-catalyzed metabolism, activation of JNK and ERK and P53/P21 up-regulation. J Nutr Biochem 24:496–504
5. Archer S (1993) Measurement of nitric oxide in biological models. FASEB J 7:349–360
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