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Human omentin-1 reduces vascular insulin resistance and hypertension in Otsuka Long-Evans Tokushima Fatty rats

  • Published:2023-11-13 Issue: Volume: Page:
  • ISSN:0028-1298
  • Container-title:Naunyn-Schmiedeberg's Archives of Pharmacology
  • language:en
  • Short-container-title:Naunyn-Schmiedeberg's Arch Pharmacol

Author:

Okamura Yuta,Adachi Ko,Niijima Ryo,Kodama Tomoko,Otani Kosuke,Okada Muneyoshi,Yamawaki Hideyuki

Funder

Kitasato University Research Grant

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology,General Medicine

Reference32 articles.

1. Alsenousy AHA, El-Tahan RA, Ghazal NA, Piñol R, Millán A, Ali LMA, Kamel MA (2022) The anti-obesity potential of superparamagnetic iron oxide nanoparticles against high-fat diet-induced obesity in rats: Possible involvement of mitochondrial biogenesis in the adipose tissues. Pharmaceutics 14(10):2134. https://doi.org/10.3390/pharmaceutics14102134

2. Dong Q, Xing W, Li K, Zhou X, Wang S, Zhang H (2021) Tetrahydroxystilbene glycoside improves endothelial dysfunction and hypertension in obese rats: The role of omentin-1. Biochem Pharmacol 186:114489. https://doi.org/10.1016/j.bcp.2021.114489

3. Kataoka Y, Shibata R, Ohashi K, Kambara T, Enomoto T, Uemura Y, Ogura Y, Yuasa D, Matsuo K, Nagata T, Oba T, Yasukawa H, Numaguchi Y, Sone T, Murohara T, Ouchi N (2014) Omentin prevents myocardial ischemic injury through AMP-activated protein kinase- and akt- dependent mechanisms. J Am Coll Cardiol 63(24):2722–2733. https://doi.org/10.1016/j.jacc.2014.03.032

4. Kazama K, Tatsuya U, Okada M, Hara Y, Yamawaki H (2012) Omentin plays an anti-inflammatory role through inhibition of TNF-α-induced superoxide production in vascular smooth muscle cells. Eur J Pharmacol 686(1–3):116–123. https://doi.org/10.1016/j.ejphar.2012.04.033

5. Kazama K, Okada M, Yamawaki H (2014) A novel adipocytokine, omentin, inhibits platelet-derived growth factor-BB-induced vascular smooth muscle cell migration through antioxidative mechanism. Am J Physiol Heart Circ Physiol 306(12):H1714–H1719. https://doi.org/10.1152/ajpheart.00048.2014

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