Cucurbitacin B induces mitochondrial-mediated apoptosis pathway in cholangiocarcinoma cells via suppressing focal adhesion kinase signaling
Author:
Funder
Thailand Research Fund
Khon Kaen University
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology,General Medicine
Link
http://link.springer.com/article/10.1007/s00210-018-1584-3/fulltext.html
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3. Cheng L, Xu PH, Shen BD, Shen G, Li JJ, Qiu L, Liu CY, Yuan HL, Han J (2015) Improve bile duct-targeted drug delivery and therapeutic efficacy for cholangiocarcinoma by cucurbitacin B loaded phospholipid complex modified with berberine hydrochloride. Int J Pharm 489:148–157
4. Guo J, Zhao W, Hao W, Ren G, Lu J, Chen X (2014) Cucurbitacin B induces DNA damage, G2/M phase arrest, and apoptosis mediated by reactive oxygen species (ROS) in leukemia K562 cells. Anti Cancer Agents Med Chem 14:1146–1153
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