Nimotuzumab therapy in the treatment of pediatric central nervous system tumors: single-center experience

Author:

Susam-Sen HilalORCID,Varan Ali,Bajin İnci,Göçmen Rahşan,Aydın Burca,Yalcin Bilgehan,Kurucu Nilgun,Kutluk Tezer,Bayhan Turhan,Akyuz Canan

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology,General Medicine

Reference24 articles.

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2. Bode U, Buchen S, Warmuth-Metz M, Pietsch T, Bach F, Fleischhack G. (2006) Final report of a phase II trial of nimotuzumab in the treatment of refractory and relapsed high-grade gliomas in children and adolescents. Journal of Clinical Oncology, 2007 ASCO Annual Meeting Proceedings Part I. Vol 25, No. 18S (June 20 Supplement), 2007

3. Bredel M, Pollack IF, Hamilton RL, James CD (1999) Epidermal growth factor receptor expression and gene amplification in high-grade non-brainstem gliomas of childhood. Clin Cancer Res 5:1786–1792

4. Cabanas R, Saurez G, Alert J, Reyes A, Valdes J, Gonzalez MC, Pedrayes JL, Valle L, Infante M, Avila M, Herrera R, Hechavarria E, Rios M, Fernández A, Lorenzo Luaces P, Crombet Ramos T (2014) Prolonged use of Nimotuzumab in children with central nervous system tumors: safety and feasibility. Cancer Biother Radiopharm 29(4):173–178

5. Crombet T, Torres L, Neninger E, Catalá M, Solano ME, Perera A, Torres O, Iznaga N, Torres F, Pérez R, Lage A (2003) Pharmacological evaluation of humanized anti-epidermal growth factor receptor, monoclonal antibody h-R3, in patients with advanced epithelial-derived cancer. J Immunother 26(2):139–148

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