A positive inotropic effect of adenosine in cardiac preparations of right atria from diseased human hearts

Author:

Gergs Ulrich,Boknik Peter,Schmitz Wilhelm,Simm Andreas,Silber Rolf-Edgar,Neumann Joachim

Publisher

Springer Science and Business Media LLC

Subject

Pharmacology,General Medicine

Reference33 articles.

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2. Behnke N, Müller W, Neumann J, Schmitz W, Scholz H, Stein B (1990) Differential antagonism by 1,3-dipropylxanthine-8-cyclopentylxanthine and 9-chloro-2(2-furanyl)-5,6-dihydro-1,2,4-triazolo (1,5-c)quinazolin-5-imine of the effects of adenosine derivatives in the presence of isoprenaline on contractile response and cAMP content in cardiomyocytes. Evidence for the coexistence of A1- and A2-adenosine receptors on cardiomyocytes. J Pharmacol Exp Ther 254:1017–1023

3. Belardinelli L, Isenberg G (1983) Isolated atrial myocytes: adenosine and acetylcholine increase potassium conductance. Am J Physiol 244:H734–H737

4. Berne RM (1963) Cardiac nucleotides in hypoxia: possible role in regulation of coronary blood flow. Am J Physiol 204:317–322

5. Böhm M, Brückner R, Hackbarth I, Haubitz B, Linhart R, Meyer W, Schmidt B, Schmitz W, Scholz H (1984) Adenosine inhibition of catecholamine-induced increase in force of contraction in guinea-pig atrial and ventricular heart preparations. Evidence against a cyclic AMP- and cyclic GMP-dependent effect. J Pharmacol Exp Ther 230:483–492

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