Geraniol ameliorates diabetic nephropathy via interference with miRNA-21/PTEN/Akt/mTORC1 pathway in rats
Author:
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology,General Medicine
Link
https://link.springer.com/content/pdf/10.1007/s00210-020-01944-9.pdf
Reference46 articles.
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2. Afkarian M, Sachs MC, Kestenbaum B, Hirsch IB, Tuttle KR, Himmelfarb J, De Boer IH (2013) Kidney disease and increased mortality risk in type 2 diabetes. J Am Soc Nephrol 24:302–308
3. Ahmad ST, Arjumand W, Seth A, Nafees S, Rashid S, Ali N, Sultana S (2011) Preclinical renal cancer chemopreventive efficacy of geraniol by modulation of multiple molecular pathways. Toxicology 290:69–81
4. Babukumar S, Vinothkumar V, Sankaranarayanan C, Srinivasan S (2017) Geraniol, a natural monoterpene, ameliorates hyperglycemia by attenuating the key enzymes of carbohydrate metabolism in streptozotocin-induced diabetic rats. Pharm Biol 55:1442–1449
5. Baltrusch S, Schmitt H, Brix A, Langer S, Lenzen S (2012) Additive activation of glucokinase by the bifunctional enzyme 6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase and the chemical activator LY2121260. Biochem Pharmacol 83:1300–1306
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