Pelargonidin alleviates acrolein-induced inflammation in human umbilical vein endothelial cells by reducing COX-2 expression through the NF-κB pathway
Author:
Funder
Nanyang Basic and Frontier Research Project
Publisher
Springer Science and Business Media LLC
Subject
Pharmacology,General Medicine
Link
https://link.springer.com/content/pdf/10.1007/s00210-023-02712-1.pdf
Reference51 articles.
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2. Chen WY, Zhang J, Ghare S, Barve S, McClain C, Joshi-Barve S (2016) Acrolein is a pathogenic mediator of alcoholic liver disease and the scavenger hydralazine is protective in mice. Cell Mol Gastroenterol Hepatol 2(5):685–700. https://doi.org/10.1016/j.jcmgh.2016.05.010
3. Cipollone F (2005) COX-2 and prostaglandins in atherosclerosis. Lupus 14(9):756–759. https://doi.org/10.1191/0961203305lu2215oa
4. Daimon M, Sugiyama K, Kameda W, Saitoh T, Oizumi T, Hirata A et al (2003) Increased urinary levels of pentosidine, pyrraline and acrolein adduct in type 2 diabetes. Endocr J 50(1):61–67. https://doi.org/10.1507/endocrj.50.61
5. Duarte LJ, Chaves VC, Nascimento M, Calvete E, Li M, Ciraolo E et al (2018) Molecular mechanism of action of Pelargonidin-3-O-glucoside, the main anthocyanin responsible for the anti-inflammatory effect of strawberry fruits. Food Chem 247:56–65. https://doi.org/10.1016/j.foodchem.2017.12.015
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