Selective detection of HBV pre-genomic RNA in chronic hepatitis B patients using a novel RT-PCR assay

Author:

Nguyen Ung Dinh,Le Do Quyen,Vu Quynh Anh Nguyen,Trieu Nguyet Thi,Dao Trang Thuy,Van Le Nam,Nguyen Son Thai,Hoang Tuyen Tien,Nguyen Chinh Trong,Nguyen Thang Hong,Van Nguyen Dien,Ho Tho HuuORCID

Funder

Hanoi Department of Science & Technology

Publisher

Springer Science and Business Media LLC

Subject

General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference25 articles.

1. Organization WH. Fact sheet: heptitis B. 2023. https: //wwwwhoint/news-room/fact-sheets/detail/hepatitis-b. Accessed 18 Apr 2023.

2. Nelson NP, Easterbrook PJ, McMahon BJ. Epidemiology of hepatitis B virus infection and impact of vaccination on disease. Clin Liver Dis. 2016;20:607–28.

3. Cloherty G, Butler E, Kuhns M. Serum hepatitis B virus RNA as a potential diagnostic biomarker during chronic hepatitis B virus infection. Clin Liver Dis. 2019;13:90–2.

4. European Association for the Study of the Liver. Electronic address EEE, European Association for the Study of the L. EASL. Clinical practice guidelines on the management of hepatitis B virus infection. J Hepatol. 2017;2017(67):370–98.

5. Tsuge M, Murakami E, Imamura M, et al. Serum HBV RNA and HBeAg are useful markers for the safe discontinuation of nucleotide analogue treatments in chronic hepatitis B patients. J Gastroenterol. 2013;48:1188–204.

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