Enzymatic activation of double-targeted 5′-O-l-valyl-decitabine prodrug by biphenyl hydrolase-like protein and its molecular design basis-Reference-Cited by-同舟云学术

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Enzymatic activation of double-targeted 5′-O-l-valyl-decitabine prodrug by biphenyl hydrolase-like protein and its molecular design basis

Published:2017-01-09 Issue:2 Volume:7 Page:304-311
ISSN:2190-393X
Container-title:Drug Delivery and Translational Research
language:en
Short-container-title:Drug Deliv. and Transl. Res.

Author:

Tao Wenhui,Zhao Dongyang,Sun Mengchi,Li Meng,Zhang Xiangyu,He Zhonggui,Sun Yinghua,Sun Jin

Funder

the National Nature Science Foundation of China

Publisher

Springer Science and Business Media LLC

Subject

Pharmaceutical Science

Link

http://link.springer.com/content/pdf/10.1007/s13346-016-0356-1.pdf

Reference39 articles.

1. Tefferi A, Vardiman JW. Myelodysplastic syndromes. N Engl J Med. 2009;361(19):1872–85.

2. Jabbour E, Issa JP, Garcia-Manero G, Kantarjian H. Evolution of decitabine development: accomplishments, ongoing investigations, and future strategies. Cancer. 2008;112(11):2341–51.

3. Choi SH, Byun HM, Kwan JM, Issa JP, Yang AS. Hydroxycarbamide in combination with azacitidine or decitabine is antagonistic on DNA methylation inhibition. Br J Haematol. 2007;138(5):616–23.

4. Fenaux P. Inhibitors of DNA methylation: beyond myelodysplastic syndromes. Nat Clin Prac Oncol. 2005;2(Suppl 1):36–44.

5. Kantarjian H, Issa JP, Rosenfeld CS, Bennett JM, Albitar M, DiPersio J, et al. Decitabine improves patient outcomes in myelodysplastic syndromes: results of a phase III randomized study. Cancer. 2006;106(8):1794–803.

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