PBPK model of pegylated liposomal doxorubicin to simultaneously predict the concentration–time profile of encapsulated and free doxorubicin in tissues
Author:
Funder
The National Natural Science Foundation of China
Publisher
Springer Science and Business Media LLC
Link
https://link.springer.com/content/pdf/10.1007/s13346-024-01680-0.pdf
Reference58 articles.
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2. Sekiya N, Imamura A. [Doxil–pegylated liposomal doxorubicin], Gan to kagaku ryoho. Cancer Chemother. 2008;35:1439–43.
3. Gabizon A, Shmeeda H, Barenholz Y. Pharmacokinetics of pegylated liposomal Doxorubicin: review of animal and human studies. Clin Pharmacokinet. 2003;42:419–36.
4. Russell LM, Hultz M, Searson PC. Leakage kinetics of the liposomal chemotherapeutic agent Doxil: The role of dissolution, protonation, and passive transport, and implications for mechanism of action. J Control Release. 2018;269:171–6.
5. Mohamed M, Abu Lila AS, Shimizu T, Alaaeldin E, Hussein A, Sarhan HA, Szebeni J, Ishida T. PEGylated liposomes: immunological responses. Sci Technol Adv Mater. 2019;20(1):710–24.
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