Engineering protein translocation and unfolded protein response enhanced human PH-20 secretion in Pichia pastoris
Author:
Funder
National Natural Science Foundation of China
Fundamental Research Funds for the Central Universities
Taishan Industry Leading Talents
Publisher
Springer Science and Business Media LLC
Link
https://link.springer.com/content/pdf/10.1007/s00253-023-12878-6.pdf
Reference58 articles.
1. Arming S, Strobl B, Wechselberger C, Kreil G (1997) In vitro mutagenesis of PH-20 hyaluronidase from human sperm. Eur J Biochem 247(3):810–814. https://doi.org/10.1111/j.1432-1033.1997.t01-1-00810.x
2. Ata-abadi NS, Forouzanfar M, Dormiani K, Varnosfaderani SR, Pirjamali L, Nasr-Esfahani MH, Hajidavaloo RM (2022) Site-specific integration as an efficient method for production of recombinant human hyaluronidase PH20 in semi-adherent cells. Appl Microbiol Biotechnol 106(4):1459–1473. https://doi.org/10.1007/s00253-022-11794-5
3. Bankefa OE, Wang M, Zhu T, Li Y (2018) Hac1p homologues from higher eukaryotes can improve the secretion of heterologous proteins in the yeast Pichia pastoris. Biotechnol Lett 40(7):1149–1156. https://doi.org/10.1007/s10529-018-2571-y
4. Besada-Lombana PB, Da Silva NA (2019) Engineering the early secretory pathway for increased protein secretion in Saccharomyces cerevisiae. Metab Eng 55:142–151. https://doi.org/10.1016/j.ymben.2019.06.010
5. Blanchard V, Gadkari RA, Gerwig GJ, Leeflang BR, Dighe RR, Kamerling JP (2007) Characterization of the N-linked oligosaccharides from human chorionic gonadotropin expressed in the methylotrophic yeast Pichia pastoris. Glycoconj J 24(1):33–47. https://doi.org/10.1007/s10719-006-9010-3
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