A stable vector for efficient production of heterologous proteins and secondary metabolites in streptomycetes

Author:

Novakova Renata,Homerova Dagmar,Csolleiova Dominika,Rezuchova Bronislava,Sevcikova Beatrica,Javorova Rachel,Feckova Lubomira,Kormanec JanORCID

Funder

Agentúra na Podporu Výskumu a Vývoja

Vedecká Grantová Agentúra MŠVVaŠ SR a SAV

Publisher

Springer Science and Business Media LLC

Subject

Applied Microbiology and Biotechnology,General Medicine,Biotechnology

Reference59 articles.

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2. Baltz RH (2016) Genetic manipulation of secondary metabolite biosynthesis for improved production in Streptomyces and other actinomycetes. J Ind Microbiol Biotechnol 43:343–370. https://doi.org/10.1007/s10295-015-1682-x

3. Bekeova C, Rehakova A, Feckova L, Vlckova S, Novakova R, Mingyar E, Kormanec J (2016) Characterisation of the genes involved in the biosynthesis and attachment of the aminodeoxysugar D-forosamine in the auricin gene cluster of Streptomyces aureofaciens CCM3239. Appl Microbiol Biotechnol 100:3177–3195. https://doi.org/10.1007/s00253-015-7214-9

4. Belknap KC, Cooper JP, Barth CJ, Andam CP (2020) Genome mining of biosynthetic and chemotherapeutic gene clusters in Streptomyces bacteria. Sci Rep 10:2003. https://doi.org/10.1038/s41598-020-58904-9

5. Bentley SD, Chater KF, Cerdeno-TarragaAM CGL, Thomson NR, James KD, Harris DE, Quail MA, Kieser H, Harper D, Bateman A, Brown S, Chandra G, Chen C, Collins M, Cronin A, Fraser A, Goble A, Hidalgo J, Hornsby T, Howarth S, Huang CH, Kieser T, Larke L, Murphy L, Oliver K, O’Neil S, Rabbinowitsch E, Rajandream MA, Rutherford K, Rutter S, Seeger K, Saunders D, Sharp S, Squares R, Squares S, Taylor K, Warren T, Wietzorrek A, Woodward J, Barrell BG, Parkhill J, Hopwood DA (2002) Complete genome sequence of the model actinomycete Streptomyces coelicolor A3(2). Nature 417:141–147. https://doi.org/10.1038/417141a

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