Co-biosynthesis of germacrene A, a precursor of β-elemene, and lycopene in engineered Escherichia coli-Reference-Cited by-同舟云学术

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Co-biosynthesis of germacrene A, a precursor of β-elemene, and lycopene in engineered Escherichia coli

Published:2022-11-14 Issue:24 Volume:106 Page:8053-8066
ISSN:0175-7598
Container-title:Applied Microbiology and Biotechnology
language:en
Short-container-title:Appl Microbiol Biotechnol

Author:

Li Meijie,Wen Qifeng,Lv Shuzhe,Yang Rumeng,Cheng Tao,Wang Zhaobao,Yang Jianming^ORCID

Funder

“First class grassland science discipline” program in Shandong Province

National Natural Science Foundation of China

the Talents of High-Level Scientific Research Foundation

Talents of High-Level Scientific Research Foundation

State Key Laboratory of Microbial Technology Open Projects Fund

CAS Key Laboratory of Biobased Materials, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences

Key Laboratory of Biofuels, Qingdao Institute of Bioenergy and Bioprocess Technology, Chinese Academy of Sciences

Publisher

Springer Science and Business Media LLC

Subject

Applied Microbiology and Biotechnology,General Medicine,Biotechnology

Link

https://link.springer.com/content/pdf/10.1007/s00253-022-12257-7.pdf

Reference49 articles.

1. Agger SA, Lopez-Gallego F, Hoye TR, Schmidt-Dannert C (2008) Identification of sesquiterpene synthases from Nostoc punctiforme PCC 73102 and Nostoc sp. strain PCC 7120. J Bacteriol 190(18):6084–6096. https://doi.org/10.1128/JB.00759-08

2. Bentley FK, García-Cerdán JG, Chen H-C, Melis A (2013) Paradigm of monoterpene (β-phellandrene) hydrocarbons production via photosynthesis in Cyanobacteria. Bioenergy Res 6(3):917–929. https://doi.org/10.1007/s12155-013-9325-4

3. Biggs BW, Lim CG, Sagliani K, Shankar S, Stephanopoulos G, De Mey M, Ajikumar PK (2016) Overcoming heterologous protein interdependency to optimize P450-mediated taxol precursor synthesis in Escherichia coli. Proc Natl Acad Sci 113(12):3209–3214. https://doi.org/10.1073/pnas.1515826113

4. Chang MCY, Keasling JD (2006) Production of isoprenoid pharmaceuticals by engineered microbes. Nat Chem Biol 2(12):674–681. https://doi.org/10.1038/nchembio836

5. Chang W-c, Song H, Liu H-w, Liu P (2013) Current development in isoprenoid precursor biosynthesis and regulation. Curr Opin Chem Biol 17(4):571–579. https://doi.org/10.1016/j.cbpa.2013.06.020

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1. Screening and modification of (+)-germacrene A synthase for the production of the anti-tumor drug (−)-β-elemene in engineered Saccharomyces cerevisiae;International Journal of Biological Macromolecules;2024-11

2. Recent advances in lycopene and germacrene a biosynthesis and their role as antineoplastic drugs;World Journal of Microbiology and Biotechnology;2024-06-25

3. Characterization of a group of germacrene A synthases involved in the biosynthesis of β-elemene from Atractylodis macrocephala;International Journal of Biological Macromolecules;2024-06

4. Two-Phase Fermentation Systems for Microbial Production of Plant-Derived Terpenes;Molecules;2024-03-02

5. Combination of microbial and chemical synthesis for the sustainable production of β‐elemene, a promising plant‐extracted anticancer compound;Biotechnology and Bioengineering;2023-09-04

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