Oxidation and reduction analysis of therapeutic recombinant human interleukin-15 by HPLC and LC-MS

Author:

Wang Yang,Chen Huanhuan,Zhao Meiqi,Feng Lei,Liu Zexin,Zeng Qiongya,Shi Wenqiang,Zhu Wen,Song Luyao,Zhu Jianwei,Lu HuiliORCID

Publisher

Springer Science and Business Media LLC

Subject

Applied Microbiology and Biotechnology,General Medicine,Biotechnology

Reference19 articles.

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3. Conlon KC, Lugli E, Welles HC, Rosenberg SA, Fojo AT, Morris JC, Fleisher TA, Dubois SP, Perera LP, Stewart DM, Goldman CK, Bryant BR, Decker JM, Chen J, Worthy TYA, Figg WD Sr, Peer CJ, Sneller MC, Lane HC et al (2015) Redistribution, hyperproliferation, activation of natural killer cells and CD8 T cells, and cytokine production during first-in-human clinical trial of recombinant human interleukin-15 in patients with cancer. J Clin Oncol 33(1):74–U123. https://doi.org/10.1200/jco.2014.57.3329

4. Cooley S, He F, Bachanova V, Vercellotti GM, DeFor TE, Curtsinger JM, Robertson P, Grzywacz B, Conlon KC, Waldmann TA, McKenna DH, Blazar BR, Weisdorf DJ, Miller JS (2019) First-in-human trial of rhIL-15 and haploidentical natural killer cell therapy for advanced acute myeloid leukemia. Blood Adv 3(13):1970–1980. https://doi.org/10.1182/bloodadvances.2018028332

5. Grabstein KH, Eisenman J, Shanebeck K, Rauch C, Srinivasan S, Fung V, Beers C, Richardson J, Schoenborn MA, Ahdieh M, Johnson L, Alderson MR, Watson JD, Anderson DM, Giri JG (1994) Cloning of a T cell growth factor that interacts with the beta chain of the interleukin-2 receptor. Science 264(5161):965–968. https://doi.org/10.1126/science.8178155

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