Efficient synthesis of bepotastine and cloperastine intermediates using engineered alcohol dehydrogenase with a hydrophobic pocket

Author:

Wu Kai,Yan Jinrong,Wang Xiaojing,Yin Xinai,Shi Guixiang,Yang Lei,Li Fangling,Huang Junhai,Shao LeiORCID

Funder

Shanghai Sailing Program

Natural Science Foundation of China

Natural Science Foundation of Shanghai

Publisher

Springer Science and Business Media LLC

Subject

Applied Microbiology and Biotechnology,General Medicine,Biotechnology

Reference29 articles.

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3. Catania MA, Cuzzocrea S (2011) Pharmacological and clinical overview of cloperastine in treatment of cough. Ther Clin Risk Manag 7:83–92

4. Dupuis P, Prokopich CL, Hynes A, Kim H (2020) A contemporary look at allergic conjunctivitis. Allergy, Asthma Clin Immunol 16:5

5. Frisch M J, Trucks G W, Schlegel H B, Scuseria G E, Robb M A, Cheeseman J R, Scalmani G, Barone V, Petersson G A, Nakatsuji H, Li X, Caricato M, Marenich A V, Bloino J, Janesko B G, Gomperts R, Mennucci B, Hratchian HP, Ortiz J V, Izmaylov AF, Sonnenberg JL, Williams, Ding F, Lipparini F, Egidi F, Goings J, Peng B, Petrone A, Henderson T, Ranasinghe D, Zakrzewski VG, Gao J, Rega N, Zheng G, Liang W, Hada M, Ehara M, Toyota K, Fukuda R, Hasegawa J, Ishida M, Nakajima T, Honda Y, Kitao O, Nakai H, Vreven T, Throssell K, Montgomery Jr, J A, Peralta JE, Ogliaro F, Bearpark MJ, Heyd JJ, Brothers EN, Kudin KN, Staroverov VN, Keith T A, Kobayashi R, Normand J, Raghavachari K, Rendell AP, Burant JC, Iyengar SS, Tomasi J, Cossi M, Millam JM, Klene M, Adamo C, Cammi R, Ochterski JW, Martin RL, Morokuma K, Farkas O, Foresman JB, Fox DJ (2016) Gaussian16 Rev. C. 01 Wallingford, CT

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