Extensive hydrolysis of phosphonates as unexpected behaviour of the known His6-organophosphorus hydrolase

Author:

Lyagin Ilya V.,Andrianova Mariia S.,Efremenko Elena N.ORCID

Funder

Ministry of Education and Science of the Russian Federation

Russian Foundation for Basic Research

Publisher

Springer Science and Business Media LLC

Subject

Applied Microbiology and Biotechnology,General Medicine,Biotechnology

Reference31 articles.

1. Ashkenazi N, Segall Y, Chen R, Sod-Moriah G, Fattal E (2010) The mechanism of nucleophilic displacements at phosphorus in chloro-substituted methylphosphonate esters: P-O vs P-C bond cleavage: a DFT study. J Org Chem 75:1917–1926. doi: 10.1021/jo9026325

2. Centers for Disease Control and Prevention, Department of Health and Human Services Review of the U.S. (2005) Army proposal for off-site treatment and disposal of caustic Vx hydrolysate from the Newport Chemical Agent Disposal Facility. A report to Congress, Washington DC

3. Christol H, Marty C (1968) Hydrolyse basique de phosphonates. II Étude Quantitative. J Organomet Chem 12:471–478. doi: 10.1016/S0022-328X(00)88700-8

4. Efremenko EN, Votchitseva YA, Aliev TK, Varfolomeev SD (2005) Recombinant plasmid DNA ptes-his-oph and producer of oligohistidine-containing organophosphate hydrolase. Russian Patent 2255975

5. Efremenko E, Votchitseva Y, Plieva F, Galaev I, Mattiasson B (2006) Purification of His6-organophosphate hydrolase using monolithic supermacroporous polyacrylamide cryogels developed for immobilized metal affinity chromatography. Appl Microbiol Biot 70:558–563. doi: 10.1007/s00253-005-0103-x

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