New strategies for drug discovery: activation of silent or weakly expressed microbial gene clusters
Author:
Publisher
Springer Science and Business Media LLC
Subject
Applied Microbiology and Biotechnology,General Medicine,Biotechnology
Link
http://www.springerlink.com/index/pdf/10.1007/s00253-012-4551-9
Reference106 articles.
1. Ahmetagic A, Pemberton JM (2011) Antibiotic resistant mutants of Escherichia coli K12 show increases in heterologous gene expression. Plasmid 65:51–57
2. Alexander DC, Rock J, He X, Brian P, Miao V, Baltz RH (2010) Development of a genetic system for combinatorial biosynthesis of lipopeptides in Streptomyces fradiae and heterologous expression of the A54145 biosynthesis gene cluster. Appl Environ Microbiol 76:6877–6887
3. Artsimovitch I, Patlan V, Sekine S, Vassylyeva MN, Hosaka T, Ochi K, Yokoyama S, Vassylyev DG (2004) Structural basis for transcription regulation by alarmone ppGpp. Cell 117:299–310
4. Baharoglu Z, Lestini R, Duigou S, Michel B (2010) RNA polymerase mutations that facilitate replication progression in the rep uvrD recF mutant lacking two accessory replicative helicases. Mol Microbiol 77:324–336
5. Baltz RH (2010) Streptomyces and Saccharopolyspora hosts for heterologous expression of secondary metabolite gene clusters. J Ind Microbiol Biotechnol 37:759–772
Cited by 254 articles. 订阅此论文施引文献 订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献
1. Improving key gene expression and di-n-butyl phthalate (DBP) degrading ability in a novel Pseudochrobactrum sp. XF203 by ribosome engineering;Science of The Total Environment;2024-10
2. Cytotoxic Peptaibols from Trichoderma guizhouense, a Fungus Isolated from an Urban Soil Sample;Journal of Natural Products;2024-08-05
3. Anticandidal activity of a wild Bacillus subtilis NAM against clinical isolates of pathogenic Candida albicans;Annals of Microbiology;2024-07-20
4. Small molecule in situ resin capture provides a compound first approach to natural product discovery;Nature Communications;2024-06-19
5. Progress in endophytic fungi secondary metabolites: biosynthetic gene cluster reactivation and advances in metabolomics;Bulletin of the National Research Centre;2024-04-23
1.学者识别学者识别
2.学术分析学术分析
3.人才评估人才评估
"同舟云学术"是以全球学者为主线，采集、加工和组织学术论文而形成的新型学术文献查询和分析系统，可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容，当前同舟云学术共收录了国内外主流学术期刊6万余种，收集的期刊论文及会议论文总量共计约1.5亿篇，并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询！咨询电话：010-8811{复制后删除}0370
www.globalauthorid.com
TOP
Copyright © 2019-2024 北京同舟云网络信息技术有限公司 京公网安备11010802033243号 京ICP备18003416号-3