Efficient mAb production in CHO cells with optimized signal peptide, codon, and UTR-Reference-Cited by-同舟云学术

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Efficient mAb production in CHO cells with optimized signal peptide, codon, and UTR

Published:2018-05-08 Issue:14 Volume:102 Page:5953-5964
ISSN:0175-7598
Container-title:Applied Microbiology and Biotechnology
language:en
Short-container-title:Appl Microbiol Biotechnol

Author:

You Min,Yang Yi,Zhong Chuanqi,Chen Fentian,Wang Xin,Jia Tianrong,Chen Yuanzhi,Zhou Bing,Mi Qingyu,Zhao Qinjian,An Zhiqiang,Luo Wenxin,Xia Ningshao

Funder

NSFC

Natural Science Foundation of Fujian Province

Publisher

Springer Science and Business Media LLC

Subject

Applied Microbiology and Biotechnology,General Medicine,Biotechnology

Link

http://link.springer.com/article/10.1007/s00253-018-8986-5/fulltext.html

Reference48 articles.

1. Anson DS, Dunning KR (2005) Codon-optimized reading frames facilitate high-level expression of the HIV-1 minor proteins. Mol Biotechnol 31(1):85–88. https://doi.org/10.1385/MB:31:1:085

2. Araujo PR, Yoon K, Ko D, Smith AD, Qiao M, Suresh U, Burns SC, Penalva LO (2012) Before it gets started: regulating translation at the 5′ UTR. Comp Funct Genomics 2012:475731. https://doi.org/10.1155/2012/475731

3. Birch JR, Racher AJ (2006) Antibody production. Adv Drug Deliv Rev 58(5–6):671–685. https://doi.org/10.1016/j.addr.2005.12.006

4. Brandis G, Hughes D (2016) The selective advantage of synonymous codon usage bias in Salmonella. PLoS Genet 12(3):e1005926. https://doi.org/10.1371/journal.pgen.1005926

5. Burgess-Brown NA, Sharma S, Sobott F, Loenarz C, Oppermann U, Gileadi O (2008) Codon optimization can improve expression of human genes in Escherichia coli: a multi-gene study. Protein Expr Purif 59(1):94–102. https://doi.org/10.1016/j.pep.2008.01.008

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