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Dissecting key residues of a C4-dicarboxylic acid transporter to accelerate malate export in Myceliophthora

  • Published:2022-12-21 Issue:2-3 Volume:107 Page:609-622
  • ISSN:0175-7598
  • Container-title:Applied Microbiology and Biotechnology
  • language:en
  • Short-container-title:Appl Microbiol Biotechnol

Author:

Wu Taju,Wang Yutao,Li JingenORCID,Tian Chaoguang

Funder

Key Project of the Ministry of Science and Technology of China

National Natural Science Foundation of China

Chinese Academy of Sciences

Tianjin Synthetic Biotechnology Innovation Capacity Improvement Project

Youth Innovation Promotion Association of the Chinese Academy of Sciences

Publisher

Springer Science and Business Media LLC

Subject

Applied Microbiology and Biotechnology,General Medicine,Biotechnology

Reference51 articles.

1. Ahn JH, Jang Y-S, Lee SY (2016) Production of succinic acid by metabolically engineered microorganisms. Curr Opin Biotechnol 42:54–66. https://doi.org/10.1016/j.copbio.2016.02.034

2. Alonso S, Rendueles M, Díaz M (2015) Microbial production of specialty organic acids from renewable and waste materials. Crit Rev Biotechnol 35(4):497–513. https://doi.org/10.3109/07388551.2014.904269

3. Berka RM, Grigoriev IV, Otillar R, Salamov A, Grimwood J, Reid I, Ishmael N, John T, Darmond C, Moisan MC, Henrissat B, Coutinho PM, Lombard V, Natvig DO, Lindquist E, Schmutz J, Lucas S, Harris P, Powlowski J, Bellemare A, Taylor D, Butler G, de Vries RP, Allijn IE, van den Brink J, Ushinsky S, Storms R, Powell AJ, Paulsen IT, Elbourne LD, Baker SE, Magnuson J, Laboissiere S, Clutterbuck AJ, Martinez D, Wogulis M, de Leon AL, Rey MW, Tsang A (2011) Comparative genomic analysis of the thermophilic biomass-degrading fungi Myceliophthora thermophila and Thielavia terrestris. Nat Biotechnol 29(10):922–927. https://doi.org/10.1038/nbt.1976

4. Brown SH, Bashkirova L, Berka R, Chandler T, Doty T, McCall K, McCulloch M, McFarland S, Thompson S, Yaver D, Berry A (2013) Metabolic engineering of Aspergillus oryzae NRRL 3488 for increased production of L-malic acid. Appl Microbiol Biotechnol 97(20):8903–8912. https://doi.org/10.1007/s00253-013-5132-2

5. Caballero D, Virrueta A, O’Hern CS, Regan L (2016) Steric interactions determine side-chain conformations in protein cores. Protein Eng Des Sel 29(9):367–376. https://doi.org/10.1093/protein/gzw027

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