Yeast cultures expressing the Ffase from Schwanniomyces occidentalis, a simple system to produce the potential prebiotic sugar 6-kestose-Reference-Cited by-同舟云学术

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Yeast cultures expressing the Ffase from Schwanniomyces occidentalis, a simple system to produce the potential prebiotic sugar 6-kestose

Published:2018-10-24 Issue:1 Volume:103 Page:279-289
ISSN:0175-7598
Container-title:Applied Microbiology and Biotechnology
language:en
Short-container-title:Appl Microbiol Biotechnol

Author:

Rodrigo-Frutos David,Piedrabuena David,Sanz-Aparicio Julia,Fernández-Lobato María^ORCID

Funder

Ministerio de Economía, Industria y Competitividad, Gobierno de España

Horizon 2020

Publisher

Springer Science and Business Media LLC

Subject

Applied Microbiology and Biotechnology,General Medicine,Biotechnology

Link

http://link.springer.com/article/10.1007/s00253-018-9446-y/fulltext.html

Reference51 articles.

1. Adamberg S, Tomson K, Vija H, Puurand M, Kabanova N, Visnapuu T, Jõgi E, Alamäe T, Adamberg K (2014) Degradation of fructans and production of propionic acid by Bacteroides thetaiotaomicron are enhanced by the shortage of amino acids. Front Nutr 5:1–21. https://doi.org/10.3389/fnut.2014.00021

2. Álvaro-Benito M, de Abreu M, Fernández-Arrojo L, Plou FJ, Jiménez-Barbero J, Ballesteros A, Polaina J, Fernández-Lobato M (2007) Characterization of a β-fructofuranosidase from Schwanniomyces occidentalis with transfructosylating activity yielding the prebiotic 6-kestose. J Biotechnol 132:75–81. https://doi.org/10.1016/j.jbiotec.2007.07.939

3. Álvaro-Benito M, de Abreu M, Portillo F, Sánz-Aparicio J, Fernández-Lobato M (2010a) New insights into the fructosyltransferase activity of Schwanniomyces occidentalis β-fructofuranosidase emerging from a non-conventional codon usage and directed mutation. Appl Environ Microbiol 76:7491–7499. https://doi.org/10.1128/AEM.01614-10

4. Álvaro-Benito M, Polo A, González B, Fernández-Lobato M, Sánz-Aparicio J (2010b) Structural and kinetic analysis of Schwanniomyces occidentalis invertase reveals a new oligomerization pattern and the role of its supplementary domain in substrate binding. J Biol Chem 285:13930–13941. https://doi.org/10.1074/jbc.M109.095430

5. Álvaro-Benito M, Sainz-Polo MA, González-Pérez D, González B, Plou FJ, Fernández-Lobato M, Sanz-Aparicio J (2012) Structural and kinetic insights reveal that the amino acid pair Gln-228/Asn-254 modulates the transfructosylating specificity of Schwanniomyces occidentalis β-fructofuranosidase, an enzyme that produces prebiotics. J Biol Chem 287:19674–19686. https://doi.org/10.1074/jbc.M112.355503

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